Among those who received the Moderna vaccine, delayed large local skin reactions were most common, occurring in 175 of 267 (66%) patients after the first dose and 31 of 102 (30%) after the second dose. COVID-19: Allergic reactions to SARS-CoV-2 vaccines - UpToDate The registry added to a recent report of zoster flare as a skin reaction associated with COVID vaccination. Madrid 28002. A new COVID-19 vaccine from Moderna targeting Omicron variants BA.4 and BA.5 will land in April. Spikevax is a vaccine used to prevent COVID-19 caused by SARS-CoV-2. "I think this is particularly interesting because it shows that the body is mounting an immune response to the vaccine, just as it does after infection with the virus," said Freeman. By Caroline Tien stroking or scratching the skin), Menstrual disorder (disease of menstrual cycle), Menstruation delayed (late menstruation cycle), Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability), Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition), Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation), Micturition urgency (urgency to pass the urine), Mobility decreased (ability to move is reduced), Monoplegia (a paralysis of a single limb), Mood swings (an extreme or rapid change in mood), Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness), Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. 2022 Sep 27;9(10):ofac499. an abnormal one at injection site), Injection site paraesthesia (abnormal skin sensations at injection site), Injection site pruritus (severe itching at injection site), Injection site urticaria (rash of round, red welts on the skin at injection site), Injection site vesicles (fluid- or air-filled cavity or sac at injection site), Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain), Joint range of motion decreased (disease of joint movement), Leukocytosis (increased white blood cells), Local reaction (reaction of any substance at the site of use), Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces), Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung), Lymphadenitis (inflammation or enlargement of a lymph node), Lymph follicular hypertrophy (an increase in the size of the lymph node follicles), Lymphoedema (localized fluid retention and tissue swelling), Malaise (a feeling of general discomfort or uneasiness), Maternal exposure before pregnancy (use of substance before pregnancy), Maternal exposure during pregnancy (use of substance during pregnancy), Mechanical urticaria (urticaria is triggered by mechanical shearing forces e.g. Frequency of the most common manifestations of local injection-site reactions, by dose, were swelling (18% and 15%), erythema (18% and 20%), and pain (24% and 18%). A shipping pallet may include up to 198 cases. official website and that any information you provide is encrypted Skin reactions to the Modern COVID-19 vaccine may look like raised red patches that are itchy and/or painful and can swell. Moderna COVID-19 6 5 : . How the Moderna Covid-19 mRNA vaccine was made so quickly - CNBC By Steven ReinbergHealthDay Reporter. We have a lot of things that are delayed hypersensitivity, like eczema, contact dermatitis, common antibiotic rashes," Blumenthal says. The site is secure. The study is based on data from the CDC and the FDA. 2021;384:403-416. THURSDAY, March 4, 2021 (HealthDay News) -- Some people given the Moderna COVID-19 vaccine may develop a reaction at the injection site that can first appear . The swelling typically goes down in about two to 11 days. QJM. Thromboses and COVID-19: reducing inflammation in addition to thromboprophylaxis. Can People With MS Get the COVID-19 Vaccine? Among them, 2 people (0.0%) have Cellulitis staphylococcal. Adults who had 2 doses of Moderna were about 94% less likely to become ill from COVID-19 than people who did not get the vaccine. It is recommended to get the second dose 28 days after the first dose to complete the vaccination course. They were discussed during the recent AAD virtual meeting and published simultaneously in the Journal of the American Academy of Dermatology. If You Have a Skin Reaction to the Moderna COVID-19 Vaccine, Don't Panic A new study finds some of them, including COVID toes, a measleslike rash and shingles also can be rare, and thankfully brief, side . Journal of the American Academy of Dermatology. If you have any further questions, ask your doctor, pharmacist or nurse. Among those who had a skin reaction after the first dose, 11 people also had a similar reaction after their second dose. Hyponatraemic encephalopathy and Vulval cellulitis - eHealthMe Global prevalence and clinical manifestations of cutaneous adverse reactions following COVID-19 vaccination: A systematic review and meta-analysis. San Sebastin de los Reyes Audio will be available later today. Eur Rev Med Pharmacol Sci. While information on effects on pregnancy or the newborn baby after vaccination during the first trimester is limited, no change to the risk for miscarriage has been seen. Cutaneous adverse reactions following COVID-19 vaccinations: A systematic review and meta-analysis. Shutterstock. Read all of this leaflet carefully before you receive this vaccine because it contains important information for you. The authors noted that it's possible that redness gets overlooked or may not be as obvious on dark skin. Would you like email updates of new search results? Erythematous, pruritic, painful, indurated plaque in a 33-year-old woman (patient 3) 7days after first dose of vaccine. Medpage Today is among the federally registered trademarks of MedPage Today, LLC and may not be used by third parties without explicit permission. 2023 Feb 20:1-4. doi: 10.1007/s13691-023-00598-7. Typical side effects include pain at the injection site, fever, fatigue, headache, muscle pain, chills and diarrhoea. pdf files, The Lancet Regional Health Southeast Asia, Statement on offensive historical content. Image, Download Hi-res But patients will have to use the . 2021;157(8):1000. doi:10.1001/jamadermatol.2021.2114. 2022 Oct;132:102898. doi: 10.1016/j.jaut.2022.102898. Bookshelf Moderna COVID-19 Vaccine Frequently Asked Questions | FDA newsGP - ATAGI gives Moderna bivalent vaccine green light - racgp.org.au Moderna COVID-19 Vaccine's Reactions and Adverse Events | CDC 2021 Elsevier Ltd. All rights reserved. Reasons Behind Breast Pain After the COVID-19 Vaccine, Psoriasis and COVID-19 Vaccine: What to Know. The reactions were first observed during a phase 3 clinical trial of the Moderna vaccine. A review of 414 skin reactions associated with the Moderna and Pfizer vaccines showed a variety of rashes, eruptions, and injection-site inflammation. Federal government websites often end in .gov or .mil. How to treat COVID-19 vaccine injection site pain. You can also apply ice for swelling and pain at the site of the shot. Moderna said the agreement also required royalty payments representing low single-digit percentages of future Covid-19 vaccine sales. Disclaimer. Administration of Moderna COVID-19 Vaccines | CDC Covid vaccine: You can't sue Pfizer or Moderna over side effects Unauthorized use of these marks is strictly prohibited. Q:. Accessibility Clipboard, Search History, and several other advanced features are temporarily unavailable. To update your cookie settings, please visit the, https://doi.org/10.1016/S2665-9913(21)00309-X, Cutaneous vasculitis following COVID-19 vaccination, https://www.governo.it/it/cscovid19/report-vaccini, View Large A case includes 12 cartons, or a total of 120 vials. Established in March 2020 to accumulate information on cutaneous manifestations of COVID-19, the registry expanded in December to include vaccine-related skin reactions, shortly after the FDA issued the first emergency use authorizations (EUAs) for the vaccines. Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection) is found to be associated with 555 drugs and 257 conditions by eHealthMe. COVID vaccines that are related to Vulval cellulitis: Vulval cellulitis in Moderna COVID Vaccine; Vulval cellulitis in Pfizer BioNTech Covid Vaccine; Vulval cellulitis in Johnson and Johnson Covid Vaccine FOIA Would you like email updates of new search results? Some reports may have incomplete information. The Moderna COVID-19 Vaccine includes the following ingredients: Active ingredient. We declare no competing interests. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Those carrying cross-reactive T cells from earlier exposure to other coronaviruses had greater immune responses after vaccination. Spikevax can be given during breastfeeding. What are the ingredients in the Moderna COVID-19 Vaccine? Covid vaccines linked to four different skin reactions - from - The Sun Moderna's coronavirus vaccine may cause alarming delayed side effects from its first dose among a portion of recipients. COVID arm; COVID-19 vaccine; T-cell mediated; delayed hypersensitivity reactions; mRNA vaccines; post-vaccination reactions; skin and soft tissue infection; treatment of COVID arm; vaccine allergy; vaccine safety. Cellulitis is a bacterial infection within deep layers of skin. If you don't remember your password, you can reset it by entering your email address and clicking the Reset Password button. MB), Help with Careers. Dont include personal or financial information like your National Insurance number or credit card details. A booster dose (0.25 mL, 50 micrograms) of Spikevax may be given at least 3 months after a primary Keywords: Anti-SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis. The study was also limited to a single medical center during a short period of time. -. There were 7 SAEs among 6 participants in the vaccine group (appendicitis, cellulitis, cellulitis orbital, type 1 diabetes mellitus, appendicitis, pyelonephritis and urosepsis). American Medical Association. Discuss appropriate individual recommendations with your See the end of section 4 for how to report side effects. If you experience severe side effects after getting a Covid vaccine, lawyers tell CNBC there is basically no one to blame in a U.S. court of law. New case reports and updated literature review. What's the New Phenomenon Called "COVID Vaccine Arm"? Registry participants collected information on the type and timing of vaccine doses and the morphology, timing, duration, and treatment of reactions. Bethesda, MD 20894, Web Policies When a COVID vaccine is injected into your arm muscle, your body starts building SARS-CoV-2 virus spike proteins. You have accepted additional cookies. Most of the reactions were mild and resolved on their own. Moderna COVID-19 vaccine: What are the side effects? - Medical News Today Epub 2020 Jul 23. While experiencing a reaction to a new vaccine can be frightening, Moderna only "reported delayed skin reactions in its large clinical trial in 0.8 percent of recipients after the first dose,. If any of the above apply to you (or you are not sure), talk to your doctor, pharmacist or nurse before you are given Spikevax. Moderna's Omicron vaccine: When it will be available and who can get it WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Of the 414 reactions documented, 83% occurred in patients vaccinated with the Moderna vaccine and 17% in patients who received the Pfizer vaccine. The condition is harmless, but may be mistaken for an infection. The mRNA COVID-19 vaccine is a lipid nanoparticle-encapsulated, nucleoside-modified mRNA vaccine that encodes the prefusion spike glycoprotein of the SARS-CoV-2 virus responsible for COVID-19. Spikevax is not recommended for children aged under 6 years. May 5, 2021. Opens in a new tab or window, Visit us on Facebook. The .gov means its official. Your doctor, pharmacist or nurse will inject the vaccine into a muscle (intramuscular injection) in your We study millions of patients and 5,000 more each day. The source was a giant welt surrounding Hoang's injection site. Please enter a term before submitting your search. Ask your pharmacist how to throw away medicines you no longer use. If you have previously had episodes of CLS, talk to a doctor before you are given Spikevax. Reply. The https:// ensures that you are connecting to the DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Lower limb lymphedema and cellulitis as a complication of COVID-19 vaccine: A case report. should be vaccinated as appropriate. doi: 10.1002/ccr3.6317. This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. Please enable it to take advantage of the complete set of features! You can change your cookie settings at any time. COVID-19 vaccine-induced cellulitis and myositis - PubMed Investigators identified no safety concerns and no evidence of vaccine-associated enhanced respiratory disease (VAERD). "There may be genetic factors at playwe know that genetics can be a risk for certain T-cell reactions to drugsbut otherwise, we dont fully understand why someone has a response while another does [not] for most drugs and vaccines.". A randomized, double-blind, placebo-controlled phase III clinical trial to evaluate the efficacy and safety of SARS-CoV-2 vaccine (inactivated, Vero cell): a structured summary of a study protocol for a randomised controlled trial. Moderna to build 150m vaccine centre in UK after NHS deal Covid Arm After Moderna or Pfizer Shot: What to Know - Healthline Kimberly Blumenthal, MD, lead author of the NEJM paper and co-director of the clinical epidemiology program in the division of rheumatology, allergy, and immunology at Massachusetts General Hospital, tells Verywell that the skin reactions can be as large as almost 20 centimeters, taking up most of the upper arm. However, the areas can also be much smaller. series in individuals 18 years of age and older. Information about storage, expiry, and use and handling are described in the section intended for healthcare professionals in the PDF. PMC Regulatory approval of Spikevax (formerly COVID-19 Vaccine Moderna) Clin Case Rep. 2022 Sep 12;10(9):e6314. GC led the study and wrote the report. Spikevax will be given to you as two 0.5 mL injections. The coronavirus (COVID-19) vaccines are safe and effective. Less commonly, patients had episodes of zoster (shingles), herpes simplex flares, and rosacea-like reactions. Successful Treatment of Delayed Localized Necrotizing Inflammatory Myositis After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine: A Case Report. The preferred site is the deltoid muscle of the upper arm. If you have any further questions on the use of this vaccine, ask your doctor, pharmacist or nurse. How well it works: Moderna's initial Phase 3 clinical data in December 2020 was similar to Pfizer-BioNTech'sat that point, both vaccines showed about 95% efficacy for prevention of COVID-19. We use some essential cookies to make this website work. Cellulitis staphylococcal is reported only by a few people who get Moderna COVID Vaccine. All information is observation-only. Written informed consent for publication was obtained from the patients. They vary in appearance and size and can sometimes cover most of the upper arm. The vaccine was co-developed by Moderna, Inc., a biotechnology company based in Cambridge, Massachusetts, and the National Institute of Allergy and Infectious Diseases (NIAID), part of the National . 2023 eHealthMe.com. Theodorou DJ, Theodorou SJ, Axiotis A, Gianniki M, Tsifetaki N. QJM. Why are my lymph nodes swollen and sore after a Pfizer or Moderna COVID Careers. eCollection 2022 Oct. Bose P, Goenka U, Moitra S, Majumdar S, Goenka MK, Sen SG. It is vital importance to rein- The Covid-19 vaccine is one example of how mRNA can be used. As Spikevax does not contain the virus, it cannot give you COVID-19. mRNA (Nucleoside-modified mRNA encoding the viral spike (S) glycoprotein of SARS-CoV-2; Lipids. Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine: supplementary appendix. Overview. The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. swelling of your lips, face, tongue or throat, Swelling/tenderness of the underarm glands on the same side as the injection site, redness at the injection site (some of which may occur approximately 9 to 11 days after the injection), Rash or hives at the injection site (some of which may occur at a median of 4 to 11 days after the injection), raised, itchy rash (urticaria) (which may occur from the time of injection and up to approximately two weeks after the injection), Temporary one sided facial drooping (Bells palsy), Swelling of the face (Swelling of the face may occur in patients who have had facial cosmetic injections. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Local injection-site reactions occurred in 54% of patients after the first Moderna dose and 70% after the second dose. Spikevax contains elasomeran, a molecule called messenger RNA (mRNA) with instructions for producing a protein from the original strain of SARS-CoV-2, the virus that causes COVID-19. "It was about eight centimeters big. Clipboard, Search History, and several other advanced features are temporarily unavailable. They were about 2.6 times as likely . If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. feeling faint or light-headed changes in your heartbeat shortness of breath wheezing swelling of your lips, face, tongue or throat hives or rash nausea or vomiting stomach pain Talk to your doctor. If you have itching, swelling, or tenderness at the injection site in the days after getting either dose of the vaccine, don't panic. As with all injectable vaccines, appropriate medical treatment and supervision must always be readily available in the event of an anaphylactic reaction following the administration of Spikevax. This will help to protect you against COVID-19. Read our, Expect Mild Side Effects From COVID-19 Vaccines, CDC Advisory Group Says, Reactions Could Be More Common Than Statistics Show, An Overview of the Moderna COVID-19 Vaccine, Psoriatic Arthritis and COVID Vaccines: What You Should Know. This means that there is more evidence to come about this vaccine. extensive swelling of the vaccinated limb, heavy menstrual bleeding (most cases appeared to be non-serious and temporary in nature). eCollection 2022 Dec. Li JC, Siglin J, Marshall MS, Stemmer-Rachamimov A, Bloom SM, Blumenthal KG. Symptoms of COVID arm include: itching, which can be intense a red or discolored rash that varies in size from quarter-sized to very large in some instances, the rash may spread to your hands or. J Prim Care Community Health. Side Effects of COVID-19 Vaccines - World Health Organization Rebecca Saff, MD, PhD, another lead author of the NEJM report and allergy fellowship director of the allergy and clinical immunology unit in the division of rheumatology, allergy, and immunology at Massachusetts General Hospital, tells Verywell that in the trial, "adverse events, including local adverse symptoms, were solicited for the seven days after the vaccine was given and unsolicited for 28 days after the vaccine, meaning that many of the more mild reactions may have been missed if they were after day seven.". For the past few Mondays, I have been asked to see the following "emergency" patients who called in with the diagnosis of cellulitis after the COVID-19 vaccination. Freeman disclosed a relevant relationship with UpToDate. J Autoimmun. -, Belouzard S, Millet JK, Licitra BN, Whittaker GR. We use cookies to help provide and enhance our service and tailor content and ads. Spikevax is also available as two adapted . Later data on real-world effectiveness for adults showed that the protection from the mRNA two-dose primary series wanes over time, but booster doses bring the immune system back to robust levels. You may need to read it again. These reactions, especially if accompanied by systemic symptoms, have been mistaken for cellulitis. Among people who had a skin reaction after the first dose and completed a survey after their second dose (609 people), 83% reported no skin reaction after their second shot. The study said they were associated with younger patients, lasted for an average of 12.7 days, appeared later in the course of COVID-19 and were associated with less severe cases of the disease. Spikevax contains less than 1 mmol (23 mg) sodium per dose and, that is to say, essentially sodium-free. The clinical features of the patients are summarised in the, All cases were investigated for laboratory abnormalities or organ involvements that are typically associated with small-vessel vasculitis. It will take only 2 minutes to fill in. JAMA Dermatol. The authors explained that the small sample size limited their ability to identify any differences in the appearance of the reaction between races and ethnicities. Cardiovascular symptoms, including faintness, syncope, altered mental status, palpitations, and hypotension. it damages the myelin sheath), Muscle contractions involuntary (uncontrolled muscle contraction), Muscle strain (an injury to a muscle in which the muscle fibres tear), Musculoskeletal chest pain (pain in chest muscle or nerve or bones), Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves), Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves), Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves), Myocarditis (inflammation of heart muscle myocardium), Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels), Nasopharyngitis (inflammation of the nasopharynx), Nausea (feeling of having an urge to vomit), Nervous system disorder (a general class of medical conditions affecting the nervous system), Neurological symptom (symptoms of nervous system disease), Neuropathy peripheral (surface nerve damage), Neutrophil count increased (excess than normal number of neutrophil a type of blood cell), Numbness and tingling (unusual prickling sensations), Ocular discomfort (a generic expression when there is lack of ease in/about the eyes), Ocular hyperaemia (an abnormally large amount of blood in eye), Oral discomfort (pain or irritation in mouth), Oropharyngeal discomfort (pain or irritation of oropharynx), Osteoarthritis (a joint disease caused by cartilage loss in a joint), Paleness (unusual lightness of skin colour), Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect), Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect), Parosmia (distortion of the sense of smell, as in smelling odours that are not present), Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery), Pericardial effusion (fluid around the heart), Pericarditis (inflammation of the pericardium), Pharyngeal hypoaesthesia (pharyngeal -abnormally decreased sensitivity), Photophobia (extreme sensitivity to light), Photopsia (presence of perceived flashes of light), Pneumonia bacterial (pneumonia associated with bacterial infection), Pollakiuria (abnormally frequent passage of relatively small quantities or urine), Polymyalgia rheumatica (pain in many muscles), Postmenopausal haemorrhage (post-menopausal bleeding), Psoriasis (immune-mediated disease that affects the skin), Pulmonary congestion (congestion in the lungs), Pulmonary embolism (blockage of the main artery of the lung), Pulmonary oedema (fluid accumulation in the lungs), Pulmonary thrombosis (scarring in the lungs), Purpura (purplish discoloration of the skin), Rash maculo-papular (red area on the skin that is covered with small confluent bumps), Rash vesicular (rash with a small bubble), Red blood cell sedimentation rate increased, Renal impairment (severely reduced kidney function), Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease), Respiratory disorder (respiratory disease), Respiratory distress (difficulty in breathing), Respiratory rate increased (excess breathing rate/min), Respiratory syncytial virus test negative, Respiratory tract congestion (blockage on respiratory system), Restless leg syndrome (a powerful urge to move your legs), Retching (strong involuntary effort to vomit), Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down), Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints), Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder), Salivary hypersecretion (excess saliva secretion), Scab (a hard coating on the skin formed during the wound healing), Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve), Scleroma (a hardened patch of tissue in the skin or mucous membranes), Seizure like phenomena (a variety of medical conditions may produce sudden episodes which have some similarities to epileptic seizures), Seizures (abnormal excessive or synchronous neuronal activity in the brain), Sepsis (a severe blood infection that can lead to organ failure and death), Septic shock (shock due to blood infection), Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin), Sinus headache (headache caused by sinus infections), Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node), Skin blushing/flushing (a sudden reddening of the face, neck), Skin discoloration - bluish (bluish colour of skin), Skin exfoliation (removal of the oldest dead skin cells), Skin induration (an abnormally hard spot or area on the skin), Speech impairment (adult) (inability to speak (adult)), Stomatitis (inflammation of mucous membrane of mouth), Stroke (sudden death of a portion of the brain cells due to a lack of oxygen), Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle), Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue), Tenderness (pain or discomfort when an affected area is touched), Tendonitis (a condition that causes pain and swelling of tendons), The flu (the flu is caused by an influenza virus), Thrombocytopenia (decrease of platelets in blood), Thrombosis (formation of a blood clot inside a blood vessel), Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)), Tremor (trembling or shaking movements in one or more parts of your body), Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation), Tunnel vision (the loss of peripheral vision with retention of central vision), Type iv hypersensitivity reaction (delayed type hypersensitivity as the reaction takes two to three days to develop), Urinary incontinence (inability to control the flow of urine and involuntary urination), Urinary retention (the inability to completely or partially empty the bladder), Urticaria (rash of round, red welts on the skin that itch intensely), Urticaria chronic (long lasting rash of round, red welts on the skin that itch intensely), Vaccination site erythema (redness around vaccination site), Vaccination site lymphadenopathy (abnormal enlargement of the lymph nodes- vaccination site), Vaccination site pruritus (severe itching of the skin at vaccination site), Vasculitis (inflammation of a blood vessel or blood vessels), Ventricular extrasystoles (premature cardiac contraction), Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart), Vitreous floaters (spots before the eyes), Wheezing (a high-pitched whistling sound made while you breath), Simvastatin and Anaemia Of Chronic Disease, Cytarabine and Therapeutic Agent Toxicity, Lansoprazole and Injection Site Urticaria, Staphylococcus Test Positive: 1 person, 50.00%, Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 50.00%, Periorbital Cellulitis (inflammation and infection of the eyelid and the skin surrounding the eye): 1 person, 50.00%, Muscle Aches (muscle pain): 1 person, 50.00%, Culture Wound Positive: 1 person, 50.00%, Cellulitis (infection under the skin): 1 person, 50.00%.